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Yan Ning is aimed at "dark matter": only the problems in scientific research are really exciting

  China News Agency, Beijing, April 25 (Reporter Pang Wuji) Yan Ning, the founding dean of the Shenzhen Academy of Medical Sciences, director of Shenzhen Bay Laboratory, and a professor at Tsinghua University at the opening ceremony of the annual meeting and plenary meeting of the 2024 Zhongguancun Forum, becauseThere is no appropriate detection method. In the world of life, there are still a large number of molecules that scientists are powerless.But she also bluntly stated that the problems in scientific research are really exciting.

  On the same day, Yan Ning was wearing a green skirt with a slow speech, but the expression was very clear.She tells how the depth and breadth of human understanding, exploration and transformation of the world with the development of science and technology continue to expand.The “hard core” speech is also very “grounded.”She made an analogy. After the breakthrough of the frozen electron microscope technology in 2013, the difficulty of analyzing the structure of the macromolecular structure from the past has changed from the past “climbing Mount Everest” to the current “climbing Taishan”.

  Although the technology has continued to improve, she admits that in the world of life, because of the lack of appropriate detection methods, and a large number of molecules are incompetent, such as metabolites, and a large number of sugar and lipids, they are also calledIt is “dark matter”.

On April 25, the annual meeting of the 2024 Zhongguancun Forum opened in Beijing.Yan Ning, the founding dean of Shenzhen Academy of Medical Sciences, director of Shenzhen Bay Laboratory, and a professor at Tsinghua University, attended the plenary meeting and gave a speech.Photo by reporter Tian Yuhao, a reporter from China News Agency

  Yan Ning said that biologists know the existence of “dark matter” because of their functions, but how much “dark matter” is or the structure, neither can it be seen nor controlled.This makes the development of vaccines and antibodies a difficult problem now.

  ”But in scientific research, these problems are truly exciting.” Yan Ning said that if these “dark substances” can be effectively monitored effectively and closely, they may find new physiological and pathological molecular marks, which helps people to benefit peopleLife and health.”My laboratory accidentally discovered a system last year that made us clear the fine structure of a large number of polysaccharides for the first time. At that moment, it really experienced a long -lost ecstasy.” Yan Ning sighed.